Football League First Division 1921/22
| Pos | Club | Pld | W | D | L | F | A | GA | Pts | Notes |
| 1st | Liverpool | 42 | 22 | 13 | 7 | 63 | 36 | 1.750 | 57 | Champions |
| 2nd | Tottenham Hotspur | 42 | 21 | 9 | 12 | 65 | 39 | 1.667 | 51 | Runners Up |
| 3rd | Burnley | 42 | 22 | 5 | 15 | 72 | 54 | 1.333 | 49 | - |
| 4th | Cardiff City | 42 | 19 | 10 | 13 | 61 | 53 | 1.151 | 43 | - |
| 5th | Aston Villa | 42 | 22 | 3 | 17 | 74 | 55 | 1.345 | 47 | - |
| 6th | Bolton Wanderers | 42 | 20 | 7 | 15 | 68 | 59 | 1.153 | 47 | - |
| 7th | Newcastle United | 42 | 18 | 10 | 14 | 59 | 45 | 1.311 | 46 | - |
| 8th | Middlesbrough | 42 | 16 | 14 | 12 | 79 | 69 | 1.145 | 46 | - |
| 9th | Chelsea | 42 | 17 | 12 | 13 | 40 | 43 | 0.930 | 46 | - |
| 10th | Manchester City | 42 | 18 | 9 | 15 | 65 | 70 | 0.929 | 45 | - |
| 11th | Sheffield United | 42 | 15 | 10 | 17 | 59 | 54 | 1.093 | 40 | - |
| 12th | Sunderland | 42 | 16 | 8 | 18 | 60 | 62 | 0.968 | 40 | - |
| 13th | West Bromwich Albion | 42 | 15 | 10 | 17 | 51 | 63 | 0.810 | 40 | - |
| 14th | Huddersfield Town | 42 | 15 | 9 | 18 | 53 | 54 | 0.981 | 39 | - |
| 15th | Blackburn Rovers | 42 | 13 | 12 | 17 | 54 | 57 | 0.947 | 38 | - |
| 16th | Preston North End | 42 | 13 | 12 | 17 | 42 | 65 | 0.646 | 38 | - |
| 17th | Arsenal | 42 | 15 | 7 | 20 | 47 | 56 | 0.839 | 37 | - |
| 18th | Birmingham | 42 | 15 | 7 | 20 | 48 | 60 | 0.800 | 37 | - |
| 19th | Oldham Athletic | 42 | 13 | 11 | 18 | 38 | 50 | 0.760 | 37 | - |
| 20th | Everton | 42 | 12 | 12 | 18 | 57 | 55 | 1.036 | 36 | - |
| 21st | Bradford City | 42 | 11 | 10 | 21 | 48 | 72 | 0.667 | 32 | ▼Relegated |
| 22nd | Manchester United | 42 | 8 | 12 | 22 | 41 | 73 | 0.562 | 28 | ▼Relegated |
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End of Season Notes |
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▼Bradford City were Relegated to the Football League Second Division |
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▼Manchester United were Relegated to the Football League Second Division |
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▲Nottingham Forest were Promoted from the Football League Second Division |
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▲Stoke were Promoted from the Football League Second Division |